Mayo Test ID DEXT Dermatopathology Consultation, Wet Tissue
Ordering Guidance
This test is only for a dermatopathology wet tissue consultation. For a dermatologic consultation on paraffin embedded tissue and slides, order PATHC / Pathology Consultation.
Shipping Instructions
Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.
Necessary Information
All requisition and supporting information must be submitted in English.
Each of the following items is required:
1. All requisitions must be labeled with:
-Patient name, date of birth and medical record number
-Name and phone number of the referring pathologist or ordering physician
-Anatomic site and collection date
2. A brief patient history is essential to achieve a consultation fully relevant to the ordering clinician’s needs.
3. Preliminary diagnosis or differential diagnosis
4. Clinical and/or dermoscopic images should be included if available. Submit with the request via Epic Care Everywhere, Mayo Clinic Image Share, or external storage device.
Specimen Required
Supplies: Dermatopathology Media (T101)
Sources: Skin or oral mucosa
Container/Tube: Screw-capped container or vial containing 10% formalin
Specimen Volume: Entire specimen
Collection Instructions: For scalp biopsies: when the differential diagnosis includes a scarring alopecia, 2 separate 4-mm punch biopsies are recommended (1 for vertical and 1 for horizontal sections). If a single scalp biopsy is received with the clinical diagnosis of a scarring alopecia, the specimen will be processed with horizontal sections.
Additional Information: STAT requests are not accepted for this test.
Useful For
Histologic diagnosis and differential diagnosis of cutaneous diseases
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
LEV2P | Level 2 Gross and microscopic | No | No |
LEV3P | Level 3 Gross and microscopic | No | No |
LEV4P | Level 4 Gross and microscopic | No | No |
Testing Algorithm
When this test is ordered, 1 of the 3 reflex tests will be performed at an additional charge. Appropriate additional stains and other ancillary testing may also be performed, at an additional charge, to determine a diagnosis.
For more information see Pathology Consultation Ordering Algorithm
Special Instructions
Method Name
Formalin-fixed tissues: Process/Embed
Serial sections: Hematoxylin and Eosin Stain/Light Microscopy
Reporting Name
Dermatopathology ConsultSpecimen Type
TissueSpecimen Minimum Volume
Size needed depends on diagnosis and size of lesion.
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Tissue | Ambient |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
Dermatopathology involves histologic examination of skin biopsy and oral mucosal specimens.
Reference Values
Diagnosis and description of microscopic findings
Interpretation
Histologic diagnosis is based primarily on interpretation of hematoxylin and eosin-stained sections. Special histochemical stains, such as alcian blue, Giemsa, or periodic acid-Schiff, may be necessary in some cases.
Interpretation is based on evaluation of patterns including architectural and cytologic details, which are included in a microscopic description.
Cautions
Specific diagnosis may require correlation with clinical information.
Clinical Reference
1. Lever WF, Schaumburg-Lever G. Histopathology of the Skin. 7th ed. JB Lippincott; 1990
2. Elder D, Elenitsas R, Ioffreda M, et al, eds. Atlas of Dermatopathology: Synopsis and Atlas of Lever's Histopathology of the Skin. 4th ed. Lippincott Williams and Wilkins; 2020
Method Description
Formalin-fixed, paraffin-embedded skin biopsy sections are stained and interpreted utilizing a bright-field microscope.(Elder DE, Elenitsas R, Rosenbach M, Murphy GF, Ruben AL, Xu X, eds. Lever's Histopathology of the Skin. 11th ed. Lippincott Williams and Wilkins; 2019)
Day(s) Performed
Monday through Friday
Report Available
3 to 5 days: Cases requiring additional material or ancillary testing may require additional time.Specimen Retention Time
IndefinitelyPerforming Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
88302 (if appropriate)
88304 (if appropriate)
88305 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
DEXT | Dermatopathology Consult | 60570-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
71139 | Interpretation | 33746-9 |
71140 | Participated in the Interpretation | No LOINC Needed |
71141 | Report electronically signed by | 19139-5 |
71142 | Addendum | 35265-8 |
71143 | Gross Description | 22634-0 |
71582 | Disclaimer | 62364-5 |
71854 | Case Number | 80398-1 |