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HelpMayo Test ID TRIGC Triglycerides, CDC, Serum
Specimen Required
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Patient Preparation:
1. Patient should fast overnight (12-14 hours) before specimen collection.
2. Patient must not consume any alcohol for 24 hours before specimen collection.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Method Name
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Enzymatic Colorimetric
Reporting Name
Triglycerides, CDC, SSpecimen Type
SerumSpecimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 60 days |
Reference Values
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Triglycerides
2-9 years:
Acceptable: <75 mg/dL
Borderline high: 75-99 mg/dL
High: ≥100 mg/dL
10-17 years:
Acceptable: <90 mg/dL
Borderline high: 90-129 mg/dL
High: ≥130 mg/dL
≥18 years:
Normal: <150 mg/dL
Borderline high: 150-199 mg/dL
High: 200-499 mg/dL
Very high: ≥500 mg/dL
Reference values have not been established for patients younger than 2 years.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
84478
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TRIGC | Triglycerides, CDC, S | 2571-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TRIGC | Triglycerides, CDC, S | 2571-8 |
Useful For
Measurement of triglycerides as part of lipoprotein profiling
Reject Due To
| Gross hemolysis | Reject |
Clinical Information
Triglycerides are esters of the trihydric alcohol, glycerol, with 3 long-chain fatty acids. They are partly synthesized in the liver and partly derived from the diet.
Interpretation
Increased plasma triglyceride levels are indicative of a metabolic abnormality and, along with elevated cholesterol, are considered a risk factor for atherosclerotic disease. Hyperlipidemia may be inherited or be associated with biliary obstruction, diabetes mellitus, nephrotic syndrome, kidney failure, or metabolic disorders related to endocrinopathies. Increased triglycerides may also be associated with alcohol consumption, sedentarism or medication-induced (eg, prednisone).
Since cholesterol and triglycerides can vary independently, measurement of both is more meaningful than the measurement of cholesterol only.
Cautions
Triglyceride result can be falsely decreased in patients with elevated levels of N-acetyl-p-benzoquinone imine (a metabolite of acetaminophen), N-acetylcysteine, and metamizole.
Clinical Reference
1. Grundy SM, Stone NJ, Bailey AL, et al: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the management of blood cholesterol: A report of the american college of cardiology/american heart association task force on clinical practice guidelines. Circulation. 2019;139(25):e1082-e1143. doi:10.1016/j.jacc.2018.11.002
2. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics. 2011;128 Suppl5(Suppl 5):S213-S256
3. Rosenson RS, Najera SD, Hegele RA. Heterozygous familial hypercholesterolemia presenting as chylomicronemia syndrome. J Clin Lipidol. 2017;11(1):294-296. doi:10.1016/j.jacl.2016.12.005
4. Hopkins PN, Brinton EA, Nanjee MN. Hyperlipoproteinemia type 3: the forgotten phenotype. Curr Atheroscler Rep. 2014;16(9):440. doi:10.1007/s11883-014-0440-2
5. Gotoda T, Shirai K, Ohta T, et al. Diagnosis and management of type I and type V hyperlipoproteinemia. J Atheroscler Thromb. 2012;19(1):1-12
6. Gonzales KM, Donato LJ, Shah P, Simha V. Measurement of apolipoprotein B levels helps in the identification of patients at risk for hypertriglyceridemic pancreatitis. J Clin Lipidol. 2021;15(1):97-103. doi:10.1016/j.jacl.2020.11.010
Method Description
Samples analyzed for triglycerides are measured by an automated enzymatic method. The chemistry includes hydrolysis of the triglycerides and phosphorylation of the resulting glycerol.(Package insert: Triglycerides Reagent. Roche Diagnostics; V13.0, 03/2022)
Day(s) Performed
Monday through Thursday, Sunday